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Dr. Lynn S. Penn

Lynn S. Penn, PhD

Department of Chemistry
Office: Disque Hall 211
Phone: 215.895.4970


  • AB, University of Pennsylvania, 1966
  • PhD, Bryn Mawr College, 1974

Curriculum Vitae:

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Research Interests:

Construction of complex and controlled polymer brushes for functional surfaces; experimental study of diffusion into polymer brushes and comparison with theoretical predictions; surface and interface chemistry, including wetting and adhesion; real-time monitoring and quantitative analysis of chemical reactions and adsorption on surfaces.

Selected Publications:

  • Xue Sha, Chengjun Sun, Xiaohe Xu, Laura Alexander, Patrick J. Loll, and Lynn S. Penn,* “Quartz Crystal Microbalance (QCM): Useful for Developing Procedures for Immobilization of Proteins on Solid Surfaces,” Anal. Chem., 84, 10298-10305 (2012).
  • Jennifer Chen, Minghong Li, Lynn Penn, Jun Xi,* "Real-time and Label-free Detection of Cellular Response to Signaling Mediated by Distinct Subclasses of Epidermal Growth Factor Receptors," Anal. Chem., 83, 3141-3146 (2011).   
  • Hyun-Su Lee and Lynn S. Penn,* “Polymer Brushes Make Nanopore Filter Membranes Size-Selective to Dissolved Polymers,” Macromolecules, 43, 565-567 (2010).   
  • Hyun-Su Lee, Mark Contarino, M. Umashankara, Arne Schön, Ernesto Freire, Amos B. Smith III,  Irwin M. Chaiken,  and Lynn S. Penn,* “Use of the Quartz Crystal Microbalance to Monitor Ligand-induced Conformational Rearrangements in HIV-1 Envelope Protein gp120,” Anal. Bioanal. Chem., 396, 1143-1152 (2010).    
  • Hyun-Su Lee and Lynn S. Penn,* “Evidence for Radius of Gyration as the Criterion for Selective Diffusion Behavior of Polymer Brushes,” Langmuir, 25, 7983-7989 (2009).