Lane is the Helen Freytag Distinguished Professor of Pediatrics in the section of Pediatric Nephrology at the University of Nebraska Medical Center. She received her M.D. from the University of Missouri-Kansas City and trained in Pediatrics at Rush Medical College in Chicago. Her fellowship in Nephrology was at University of Minnesota. Lane joined the faculty at UNMC in 1998 and became the Associate Chair for Research for the Department of Pediatrics in 2000. In 2008, the American Society of Nephrology selected her as founding editor of ASN Kidney News, its national magazine.
Lane is a member of many professional organizations in Nephrology and associated scientific disciplines. She performs and publishes both basic and clinical research, teaches in the lecture hall and clinic, and cares for patients in her specialty. Other interests include faculty development, particularly writing skills, and the evolving role of social media in medicine and science.