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The Barson Lab Publications

Please visit PubMed for a full list of publications.

Selected Publications

"Neurotensin in the posterior thalamic paraventricular nucleus: inhibitor of pharmacologically relevant ethanol drinking"
Pandey S, Badve PS, Curtis GR, Leibowitz SF & Barson JR
Addict Biol. [Epub ahead of print] (2017)

"Substance P in the Anterior Thalamic Paraventricular Nucleus: Role in Ethanol Drinking in Relation to Orexin From the Hypothalamus"
Barson JR, Poon K, Ho HT, Alam M, Sanzalone L & Leibowitz SF
Addict Biol, 22(1): 58-69 (2017)

"GABA-Induced Inactivation of Thalamic Paraventricular Nucleus Subregions Has Distinct Effects on Emotional Behavior"
Barson JR & Leibowitz SF
Neurosci Lett, 609, 92-6. (2015)

"Hypothalamic Neuropeptide Signaling in Alcohol Addiction"
Barson JR & Leibowitz SF
Prog Neuropsychopharmacol Biol Psychiatry, 65, 321-9 (2016)

"Anterior Thalamic Paraventricular Nucleus Is Involved in Intermittent Access Ethanol Drinking: Role of Orexin Receptor 2"
Barson JR, Ho HT & Leibowitz SF
Addict Biol, 20(3), 469-81 (2015)

"Hypothalamic Peptides Controlling Alcohol Intake: Differential Effects on Microstructure of Drinking Bouts"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol, 48(7), 657-64 (2014)

"Common Effects of Fat, Ethanol, and Nicotine on Enkephalin in Discrete Areas of the Brain"
Chang G-Q, Karatayev O, Barson JR, Liang SC & Leibowitz SF
Neuroscience, 277, 665-78 (2014)

"Differential Role of D1 and D2 Receptors in the Perifornical Lateral Hypothalamus in Controlling Ethanol Drinking and Food Intake: Possible Interaction With Local Orexin Neurons"
Chen Y-W, Morganstern I, Barson JR, Hoebel BG & Leibowitz SF
Alcohol Clin Exp Res, 38(3), 777-86 (2014)

"Complementary Roles of Orexin and Melanin-Concentrating Hormone in Feeding Behavior"
Barson JR, Morganstern I & Leibowitz SF
Int J Endocrinol, 2013(983964), 1-10 (2013)

"Opioids in the Perifornical Lateral Hypothalamus Suppress Ethanol Drinking"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol, 47(1), 31-8 (2013)

"Glutamatergic Input to the Lateral Hypothalamus Stimulates Ethanol Intake: Role of Orexin and Melanin-Concentrating Hormone"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol Clin Exp Res, 37(1), 123-31 (2013)

"Neurochemical Heterogeneity of Rats Predicted by Different Measures to Be High Ethanol Consumers"
Barson JR, Fagan SE, Chang G-Q & Leibowitz SF
Alcohol Clin Exp Res, 37(S1), E141-51 (2013)

"Effect of Dietary Fatty Acid Composition on Food Intake, Triglycerides, and Hypothalamic Peptides"
Barson JR, Karatayev O, Gaysinskaya O, Chang G-Q & Leibowitz SF
Regul Pept, 173(1-3), 13-20 (2012)

"Galanin and the Orexin 2 Receptor as Possible Regulators of Enkephalin in the PVN: Relation to Dietary Fat"
Barson JR, Chang G-Q, Poon K, Morganstern I & Leibowitz SF
Neuroscience, 193, 10-20 (2011)

"Reduced accumbens dopamine in Sprague-Dawley rats prone to overeating a fat-rich diet"
Rada PV, Bocarsly ME, Barson JR, Hoebel BG & Leibowitz SF
Physiol Behav, 101(3), 394-400 (2010)

"Role of Melanin-Concentrating Hormone in the Control of Ethanol Consumption: Region-Specific Effects Revealed by Expression and Injection Studies"
Morganstern I, Chang G-Q, Chen Y-W, Barson JR, Zhiyu Y, Hoebel BG & Leibowitz SF
Physiol Behav, 101(4), 428-37 (2010)

"Increased Enkephalin in Rats Prone to Overconsuming a Fat-Rich Diet"
Chang G-Q, Karatayev O, Barson JR, Chang S-Y & Leibowitz SF
Physiol Behav, 101(3), 360-9 (2010)

"Predictors of Ethanol Consumption in Sprague-Dawley Rats: Relation to Hypothalamic Peptides That Stimulate Ethanol Intake"
Karatayev O, Barson JR, Carr AJ, Baylan J, Chen Y-W & Leibowitz SF
Alcohol, 44(4), 323-334 (2010)

"Differential Effects of Acute and Chronic Ethanol Exposure on Orexin Expression in the Perifornical Lateral Hypothalamus"
Morganstern I, Chang G-Q, Barson JR, Ye Z, Karatayev O & Leibowitz SF
Alcohol Clin Exp Res, 34(5), 886-96 (2010)

"Effect of Chronic Ethanol on Enkephalin in the Hypothalamus and Extra-Hypothalamic Areas"
Chang G-Q, Barson JR, Karatayev O, Chang S-Y, Chen Y-W & Leibowitz SF
Alcohol Clin Exp Res, 34(5), 761-70 (2010)

"Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake"
Barson JR, Carr AJ, Soun JE, Sobhani NC, Leibowitz SF & Hoebel BG
Alcohol Clin Exp Res, 34(2), 214-22 (2010)

"Opioids in the Hypothalamus Control Dopamine and Acetylcholine Levels in the Nucleus Accumbens"
Rada PV, Barson JR, Leibowitz SF & Hoebel BG
Brain Res, 1312, 1-9 (2009)

"Opioids in the Nucleus Accumbens Stimulate Ethanol Intake"
Barson JR, Carr AJ, Soun JE, Sobhani NC, Leibowitz SF & Hoebel BG
Physiol Behav, 98(4), 453-9 (2009)

"Positive Relationship Between Dietary Fat, Ethanol Intake, Triglycerides, and Hypothalamic Peptides: Counteraction by Lipid-Lowering Drugs"
Barson JR, Karatayev O, Chang G-Q, Johnson DF, Bocarsly ME, Hoebel BG & Leibowitz SF
Alcohol, 42(6), 433-41 (2009)

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Original Research

"Involvement of the CXCL12 System in the Stimulatory Effects of Prenatal Exposure to High-Fat Diet on Hypothalamic Orexigenic Peptides and Behavior in Offspring"
Poon K, Barson JR, Shi H, Chang GQ & Leibowitz SF
Front Behav Neurosci, 11:91 (2016)

"Substance P in the Anterior Thalamic Paraventricular Nucleus: Role in Ethanol Drinking in Relation to Orexin From the Hypothalamus"
Barson JR, Poon K, Ho HT, Alam M, Sanzalone L & Leibowitz SF
Addict Biol, 22(1): 58-69 (2017)

"Relationship of the Chemokine, CXCL12, to Effects of Dietary Fat on Feeding-Related Behaviors and Hypothalamic Neuropeptide Systems"
Poon K, Barson JR, Ho HT & Leibowitz SF
Front Behav Neurosci, 10:51 (2016)

"GABA-Induced Inactivation of Thalamic Paraventricular Nucleus Subregions Has Distinct Effects on Emotional Behavior"
Barson JR & Leibowitz SF
Neurosci Lett, 609, 92-6 (2015)

"Regulation of the Orexigenic Neuropeptide, Enkepahlin, by PPAR δ And Fatty Acids in Neurons of the Hypothalamus and Forebrain"
Poon K, Alam M, Karatayev O, Barson JR & Leibowitz SF
J Neurochem, 135(5): 918-31 (2015)

"Anterior Thalamic Paraventricular Nucleus Is Involved in Intermittent Access Ethanol Drinking: Role of Orexin Receptor 2"
Barson JR, Ho HT & Leibowitz SF
Addict Biol, 20(3), 469-81 (2015)

"Stimulatory Role of the Chemokine CCL2 in Migration and Peptide Expression of Hypothalamic Neurons"
Poon K, Ho HT, Barson JR & Leibowitz SF
J Neurochem, 131(4), 509-20 (2014)

"Hypothalamic Peptides Controlling Alcohol Intake: Differential Effects on Microstructure of Drinking Bouts"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol, 48(7), 657-64 (2014)

"Common Effects of Fat, Ethanol, and Nicotine on Enkephalin in Discrete Areas of the Brain"
Chang G-Q, Karatayev O, Barson JR, Liang, SC, & Leibowitz SF
Neuroscience, 277, 665-78 (2014)

"Differential Role of D1 and D2 Receptors in the Perifornical Lateral Hypothalamus in Controlling Ethanol Drinking and Food Intake: Possible Interaction With Local Orexin Neurons"
Chen Y-W, Morganstern I, Barson JR, Hoebel BG & Leibowitz SF
Alcohol Clin Exp Res, 38(3), 777-86 (2014)

"Prenatal Exposure to Dietary Fat Induces Changes in the Transcriptional Factors, TEF and YAP, Which May Stimulate Differentiation of Peptide Neurons in Rat Hypothalamus"
Poon K, Mandava S, Chen K, Barson JR, Buschlen S & Leibowitz SF
PLOS ONE, 8(10), e77668 (2013)

"Opioids in the Perifornical Lateral Hypothalamus Suppress Ethanol Drinking"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol, 47(1), 31-8 (2013)

"Glutamatergic Input to the Lateral Hypothalamus Stimulates Ethanol Intake: Role of Orexin and Melanin-Concentrating Hormone"
Chen Y-W, Barson JR, Chen A, Hoebel BG & Leibowitz SF
Alcohol Clin Exp Res, 37(1), 123-31 (2013)

"Neurochemical Heterogeneity of Rats Predicted by Different Measures to Be High Ethanol Consumers"
Barson JR, Fagan SE, Chang G-Q & Leibowitz SF
Alcohol Clin Exp Res, 37(S1), E141-51 (2013)

"Developmental Changes in Embryonic Hypothalamic Neurons During Prenatal Fat Exposure"
Poon K, Barson JR, Fagan SE & Leibowitz SF
Am J Physiol Endocrinol Metab, 303(3), E432-41 (2012)

"Prenatal Ethanol Exposure Stimulates Neurogenesis in Hypothalamic and Limbic Peptide Systems: Possible Mechanism for Offspring Ethanol Overconsumption"
Chang G-Q, Karatayev O, Liang SC, Barson JR & Leibowitz SF
Neuroscience, 222, 417-28 (2012)

"Effect of Dietary Fatty Acid Composition on Food Intake, Triglycerides, and Hypothalamic Peptides"
Barson JR, Karatayev O, Gaysinskaya O, Chang G-Q & Leibowitz SF
Regul Pept, 173(1-3), 13-20 (2012)

"A High-Fat Meal, or Intraperitoneal Administration of a Fat Emulsion, Increases Extracellular Dopamine in the Nucleus Accumbens"
Rada P, Avena NM, Barson JR, Hoebel BG & Leibowitz SF
Brain Sci, 2(2), 242-53 (2012)

"Effects of Perinatal Exposure to Palatable Diets on Body Weight and Sensitivity to Drugs of Abuse in Rats"
Bocarsly ME, Barson JR, Hauca J, Hoebel BG, Leibowitz SF & Avena NM
Physiol Behav, 107(4), 568-75 (2012)

"Galanin and the Orexin 2 Receptor as Possible Regulators of Enkephalin in the PVN: Relation to Dietary Fat"
Barson JR, Chang G-Q, Poon K, Morganstern I & Leibowitz SF
Neuroscience, 193, 10-20 (2011)

"Reduced Accumbens Dopamine in Sprague-Dawley Rats Prone to Overeating a Fat-Rich Diet"
Rada PV, Bocarsly ME, Barson JR, Hoebel BG & Leibowitz SF
Physiol Behav, 101(3), 394-400 (2010)

"Role of Melanin-Concentrating Hormone in the Control of Ethanol Consumption: Region-Specific Effects Revealed by Expression and Injection Studies"
Morganstern I, Chang G-Q, Chen Y-W, Barson JR, Zhiyu Y, Hoebel BG & Leibowitz SF
Physiol Behav, 101(4), 428-37 (2010)

"Increased Enkephalin in Rats Prone to Overconsuming a Fat-Rich Diet"
Chang G-Q, Karatayev O, Barson JR, Chang S-Y & Leibowitz SF
Physiol Behav, 101(3), 360-9 (2010)

"Predictors of Ethanol Consumption in Sprague-Dawley Rats: Relation to Hypothalamic Peptides That Stimulate Ethanol Intake"
Karatayev O, Barson JR, Carr AJ, Baylan J, Chen Y-W & Leibowitz SF
Alcohol, 44(4), 323-334 (2010)

"Differential Effects of Acute and Chronic Ethanol Exposure on Orexin Expression in the Perifornical Lateral Hypothalamus"
Morganstern I, Chang G-Q, Barson JR, Ye Z, Karatayev O & Leibowitz SF
Alcohol Clin Exp Res, 34(5), 886-96 (2010)

"Effect of Chronic Ethanol on Enkephalin in the Hypothalamus and Extra-Hypothalamic Areas"
Chang G-Q, Barson JR, Karatayev O, Chang S-Y, Chen Y-W & Leibowitz SF
Alcohol Clin Exp Res, 34(5), 761-70 (2010)

"Opioids in the Hypothalamic Paraventricular Nucleus Stimulate Ethanol Intake"
Barson JR, Carr AJ, Soun JE, Sobhani NC, Leibowitz SF & Hoebel BG
Alcohol Clin Exp Res, 34(2), 214-22 (2010)

"Opioids in the hypothalamus control dopamine and acetylcholine levels in the nucleus accumbens"
Rada PV, Barson JR, Leibowitz SF & Hoebel BG
Brain Res, 1312, 1-9 (2009)

"Hypothalamic Injection of Non-Opioid Peptides Increases Gene Expression of the Opioid Enkephalin in Hypothalamic and Mesolimbic Nuclei: Possible Mechanism Underlying Their Behavioral Effects"
Karatayev O, Barson JR, Chang G-Q & Leibowitz SF
Peptides, 30(12), 2423-31 (2009)

"Opioids in the Nucleus Accumbens Stimulate Ethanol Intake"
Barson JR, Carr AJ, Soun JE, Sobhani NC, Leibowitz SF & Hoebel BG
Physiol Behav, 98(4), 453-9 (2009)

"Positive Relationship Between Dietary Fat, Ethanol Intake, Triglycerides, and Hypothalamic Peptides: Counteraction by Lipid-Lowering Drugs"
Barson JR, Karatayev O, Chang G-Q, Johnson DF, Bocarsly ME, Hoebel BG & Leibowitz SF
Alcohol, 42(6), 433-41 (2009)

"Delayed Suppression of Hippocampal Cell Proliferation in Rats Following Inescapable Shocks"
Fornal CA, Stevens J, Barson JR, Blakley GG, Patterson-Buckendahl P & Jacobs BL
Brain Res, 1130, 48-53 (2007)

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Reviews

"Hypothalamic Neuropeptide Signaling in Alcohol Addiction"
Barson JR & Leibowitz SF
Prog Neuropsychopharmacol Biol Psychiatry, 65, 321-9 (2016)

"Complementary Roles of Orexin and Melanin-Concentrating Hormone in Feeding Behavior"
Barson JR, Morganstern I & Leibowitz SF
Int J Endocrinol, 2013(983964), 1-10 (2013)

"Neurobiology of Consummatory Behavior: Mechanisms Underlying Overeating and Drug Use"
Barson JR, Morganstern I & Leibowitz SF
ILAR J, 53(1), 35-58 (2012)

"Regulation of Drug and Palatable Food Overconsumption by Similar Peptide Systems"
Morganstern I, Barson JR & Leibowitz SF
Curr Drug Abuse Res, 4(3), 163-73 (2011)

"Similarities in Hypothalamic and Mesocorticolimbic Circuits Regulating the Overconsumption of Food and Alcohol"
Barson JR, Morganstern I & Leibowitz SF
Physiol Behav, 104(1), 128-37 (2011)

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Chapters

"Galanin and Ingestive Behavior"
Barson JR, Morganstern I & Leibowitz SF
In Handbook of Biologically Active Peptides, 2nd Ed, SC Woods & AJ Kastin (eds), San Diego: Elsevier, Chapter 147 (2013)

"Predicting and Classifying Rats Prone to Overeating Fat"
Morganstern I, Barson JR & Leibowitz SF
In Animal Models of Eating Disorders, Neuromethods, vol 74, NM Avena (ed), New York: Humana Press, Chapter 6 (2012)

"Prenatal Programming of Obesity: Role of Macronutrient-Specific Peptide Systems"
Morganstern I, Barson JR & Leibowitz SF
In Food and Addiction: A Comprehensive Handbook, KD Brownell & MS Gold (eds), New York: Oxford University Press, Chapter 17 (2012)

"Galanin and Consummatory Behavior: Special Relationship With Dietary Fat, Alcohol and Circulating Lipids"
Barson JR, Morganstern I & Leibowitz SF
In Galanin, T. Hökfelt (ed), Experientia Supplementum Vol 102, 87-111 (2010)

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Neuropeptide disturbances images from the Barson Lab at Drexel University College of Medicine.