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The Baas Lab Publications

2018

Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains.
Qiang L, Sun X, Austin TO, Muralidharan H, Jean DC, Liu M, Yu W, Baas PW.
Curr Biol. 2018 Jul 9;28(13):2181-2189.e4. doi: 10.1016/j.cub.2018.05.045. Epub 2018 Jun 28. PMID: 30008334

Polarity Sorting of Microtubules in the Axon.
Rao AN, Baas PW.
Trends Neurosci. 2018 Feb;41(2):77-88. doi: 10.1016/j.tins.2017.11.002. Epub 2017 Nov 30. Review. PMID: 29198454

2017

"Mutant spastin proteins promote deficits in axonal transport through an isoform-specific mechanism"
Leo L, Weissmann C, Burns M, Kang M, Song Y, Qiang L, Brady ST, Baas PW, and Morfini G
Human Molecular Genetics, Vol.26, Issue.12, Pgs 2321–2334, https://doi.org/10.1093/hmg/ddx125 (April 2017)

"Truncating mutations of SPAST associated with hereditary spastic paraplegia indicate greater accumulation and toxicity of the M1 isoform of spastin" [PDF]
Solowska JM, Rao AN, and Baas PW
Molecular Biology of the Cell 28(13):1728-1737. doi:10.1091/mbc.E17-01-0047 (May 2017)

"Polarity sorting of axonal microtubules: a computational study" [PDF]
Craig EM, Yeung HT, Rao AN, and Baas PW
Molecular Biology of the Cell 28(23):3271-3285. doi:10.1091/mbc.E17-06-0380 (November 2017)

"Nanoparticle Delivery of Fidgetin siRNA as a Microtubule-based Therapy to Augment Nerve Regeneration" [PDF]
Austin TO, Matamoros AJ, Friedman JM, Friedman AJ, Nacharaju P, Yu W, Sharp DJ & Baas PW
Scientific Reports, 7:9675, DOI:10.1038/s41598-017-10250-z (August 2017)

"Cytoplasmic Dynein Transports Axonal Microtubules in a Polarity-Sorting Manner" [PDF]
Rao AN, Patil A, Black MM, Craig EM, Myers KA, Yeung HT & Baas PW
Cell Reports, 19, 2210–2219 (June 2017)

"Pharmacologically increasing microtubule acetylation corrects stress-exacerbated effects of organophosphates on neurons"
Rao AN, Patil A, Brodnik ZD, Qiang L, España RA, Sullivan KA, Black MM, Baas PW
Traffic, 18(7):433-441. doi: 10.1111/tra.12489. Epub 2017 May 25 (July 2017)

"Reprogramming cells from Gulf War veterans into neurons to study Gulf War illness"
Qiang L, Rao AN, Mostoslavsky G, James MF, Comfort N, Sullivan K, Baas PW
Neurology, 88(20):1968-1975. doi: 10.1212/WNL.0000000000003938 (May 16, 2017)

2016

Microtubules in Health and Degenerative Disease of the Nervous System [PDF]
Matamoros AJ, Baas PW
Brain Res Bull. 126(Pt 3):217-225. doi: 10.1016/j.brainresbull.2016.06.016. Epub 2016 Jun 27. (September 2016)

"Stability Properties of Neuronal Microtubules" [PDF]
Baas PW, Rao AN, Matamoros AJ, Leo L
Cytoskeleton, 73:442–460 (September 2016)

"Sliding of Centrosome-Unattached Microtubules Defines Key Features of Neuronal Phenotype" [PDF]
Rao AN, Falnikar A, O'Toole ET, Morphew MK, Hoenger A, Davidson MW, Yuan X, Baas PW
The Journal of Cell Biology. 2016. jcb-201506140.

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2011-2015

"Using SiRNA to Study Microtubule-Related Proteins in Cultured Neurons"
Leo L, Yu W, Baas PW
Methods in Cell Biology. 2015.

"Vertebrate Fidgetin Restrains Axonal Growth by Severing Labile Domains of Microtubules" [PDF]
Leo L, Yu W, D'Rozario M, Waddell EA, Marenda DR, Baird MA, Davidson MW, Zhou B, Wu B, Baker L, Sharp DJ
Cell Reports. 2015. 12(11):1723-30.

International Meeting Molecular Neurodegeneration: "News and Views in Molecular Neuroscience in Health and Disease" [PDF]
Delmenhorst, Germany, July 20–22, 2015
Gozes I, Baas PW, Richter-Landsberg C
Journal of Molecular Neuroscience. 2015. 57(2):153-9.

"Ablation of the 14-3-3gamma Protein Results in Neuronal Migration Delay and Morphological Defects in the Developing Cerebral Cortex" [PDF]
Wachi T, Cornell B, Marshall C, Zhukarev V, Baas PW, Toyo-oka K
Developmental Neurobiology. 2015.

"TPX2 Regulates Neuronal Morphology Through Kinesin-5 Interaction" [PDF]
Kahn OI, Ha N, Baird MA, Davidson MW, Baas PW
Cytoskeleton (Hoboken). 2015. 72(7):340-8.

"Inhibition of Kinesin-5 Improves Regeneration of Injured Axons by a Novel Microtubule-Based Mechanism" [PDF]
Baas PW, Matamoros AJ
Neural Regeneration Research. 2015. 10(6):845-9.

"Hereditary Spastic Paraplegia SPG4: What Is Known and Not Known About the Disease" [PDF]
Solowska JM, Baas PW
Brain. 2015. 138(Pt 9):2471-84.

"Emerging Microtubule Targets in Glioma Therapy" [PDF]
Katsetos CD, Reginato MJ, Baas PW, D'Agostino L, Legido A, Tuszyn Ski JA, Dráberová E, Dráber P
Seminars in Pediatric Neurology. 2015. 22(1):49-72.

"Histone Acetylation Inhibitors Promote Axon Growth in Adult Dorsal Root Ganglia Neurons" [PDF]
Lin S, Nazif K, Smith A, Baas PW, Smith GM
Journal of Neuroscience Research. 2015. 93(8):1215-28.

"Pharmacologically Inhibiting Kinesin-5 Activity With Monastrol Promotes Axonal Regeneration Following Spinal Cord Injury" [PDF]
Xu C, Klaw MC, Lemay MA, Baas PW, Tom VJ
Experimental Neurology. 2015. 263:172-6.

"Inhibitors of Mitotic Kinesins for Cancer Treatment: Consequences for Neurons"
Kahn OI, Baas PW
Kinesins and Cancer. F.S.B.F. Kozielski, Springer Netherlands. 2015. 251-267.

"Microtubules: Organization and Function in Neurons Introductory Article"
P.W. Baas, K.A. Myers, L. Qiang, V.C. Nadar
In: Reference Module in Biomedical Sciences. 2014. pub: Elsevier B.V.

"Kinesin-12 Influences Axonal Growth During Zebrafish Neural Development" [PDF]
Xu M, Liu D, Dong Z, Wang X, Wang X, Liu Y, Baas PW, Liu M
Cytoskeleton (Hoboken). 2014. 71(10):555-63.

"Beyond Taxol: Microtubule-Based Strategies for Promoting Nerve Regeneration After Injury" [PDF]
Baas PW
Neural Regeneration Research. 2014. 9(13):1265-6.

"Effects of Kinesin-5 Inhibition on Dendritic Architecture and Microtubule Organization" [PDF]
Kahn OI, Sharma V, Gonzalez-Billault C, Baas PW
Molecular Biology of the Cell. 2014. 26(1):66-77.

"Pathogenic Mutation of Spastin Has Gain-Of-Function Effects on Microtubule Dynamics" [PDF]
Solowska JM, D'Rozario M, Jean DC, Davidson MW, Marenda DR, Baas PW
The Journal of Neuroscience. 2014. 34(5):1856-1867.

"The Crystal Structure and Biochemical Characterization of Kif15: A Bifunctional Molecular Motor Involved in Bipolar Spindle Formation and Neuronal Development" [PDF]
Klejnot M, Falnikar A, Ulaganathan V, Cross RA, Baas PW, Kozielski F
Biological Crystallography. Acta Crystallographica Section D Biological Crystallography. 2014. 70(1):123-133.

"Neuronal Migration Re-Purposes Mechanisms of Cytokinesis" [PDF]
Falnikar A, Baas PW
Cell Cycle. 2013. 12(23):3577-3578.

"It Cuts Two Ways: Microtubule Loss During Alzheimer Disease" [PDF]
Jean DC, Baas PW
The EMBO Journal. 2013. 32:2900-2902.

"Beyond Taxol: Microtubule-Based Treatment of Disease and Injury of the Nervous System" [PDF]
Baas PW, Ahmad FJ
Brain. 2013. 136:2937–2951.

"USP47 and C Terminus of Hsp70-Interacting Protein (CHIP) Antagonistically Regulate Katanin-p60-Mediated Axonal Growth" [PDF]
Yang SW, Oh KH, Park E, Chang HM, Park JM, Seong MW, Ka SH, Song WK, Park DE, Baas PW, Jeon YJ, Chung CH
Journal of Neuroscience. 2013. 33(31):12728-38.

"Polarity in Migrating Neurons Is Related to a Mechanism Analogous to Cytokinesis" [PDF]
Falnikar A, Tole S, Liu M, Liu JS, Baas PW
Current Biology. 2013. 23(13):1215-20.

"Microtubule Stability in the Axon: New Answers to an Old Mystery" [PDF]
Baas PW
Neuron. 2013. 78(1):p.3-5.

"A Re-evaluation of the Neuronal Centrosome as a Generator of Microtubules for Axons and Dendrites" [PDF]
Baas PW, Falnikar
The Centrosome. Humana Press. 2012. Chapter 18:p.309-326.

"A Novel Role for Doublecortin and Doublecortin-Like Kinase in Regulating Growth Cone Microtubules" [PDF]
Jean DC, Baas PW, Black MM
Human Molecular Genetics 2012. 21(26):p.5511-27.

"Mitotic Motors Coregulate Microtubule Patterns in Axons and Dendrites" [PDF]
Lin S, Liu M, Mozgova OI, Yu W, Baas PW
Journal of Neuroscience 2012. 32(40):p.14033-49.

"A Gathering of Neuronal Cytoskeletal Scientists in South America" [PDF]
Baas PW, Gonzalez-Billault C
Cytoskeleton (Hoboken), 2012.

"Septin-Driven Coordination of Actin and Microtubule Remodeling Regulates the Collateral Branching of Axons" [PDF]
Hu J, Bai X, Bowen JR, Dolat L, Korobova F, Yu W, Baas PW, Svitkina T, Gallo G, Spiliotis ET
Current Biology. 2012. 22(12):1109-15.

"Partial Interruption of Axonal Transport Due to Microtubule Breakage Accounts for the Formation of Periodic Varicosities After Traumatic Axonal Injury" [PDF]
Tang-Schomer MD, Johnson VE, Baas PW, Stewart W, Smith DH
Experimental Neurology. 2012. 233(1):364-72.

"Microtubule Redistribution in Growth Cones Elicited by Focal Inactivation of Kinesin-5" [PDF]
Nadar VC, Lin S, Baas PW
Journal of Neuroscience. 2012 Apr 25. 32(17):5783-5794.

"A Novel Role for Retrograde Transport of Microtubules in the Axon" [PDF]
Baas PW, Mozgova OI
Cytoskeleton (Hoboken). 2012. 69(7):p.416-25.

"The Cytoskeleton of the Neuron - an Essay in Celebration of Paul Letourneau's Career
Jean DC, Black MM, Baas PW
Developmental Neurobiology. 2011. 71:p.790-4.

"Microtubule-Severing ATPase Spastin in Glioblastoma: Increased Expression in Human Glioblastoma Cell Lines and Inverse Roles in Cell Motility and Proliferation" [PDF]
Dra´berova´ E, Stanislav V, Morfini G, Liu PS, Sla´dkova´ V, Sulimenko T, Burns MR, Solowska J, Kulandaivel K, Chadare´vian JP, Legido A, Mo¨rk SJ, Jana´cek J, Baas PW, Dra´ber P, Katsetos CD
Journal of Neuropathology & Experimental Neurology. 2011 Sep;70(9):811-826.

"Hooks and Comets: The Story of Microtubule Polarity Orientation in the Neuron" [PDF]
Baas PW, Lin S
Developmental Neurobiology. June 21;71(6):403-418.

"Kinesin-5, a Mitotic Microtubule-Associated Motor Protein, Modulates Neuronal Migration" [PDF]
Falnikar A, Tole S, Baas PW
Molecular Biology of the Cell (MBoC). 2011 May 1;22:1561-1574.

"Inhibition of Kinesin-5, a Microtubule-Based Motor Protein, as a Strategy for Enhancing Regeneration of Adult Axons" [PDF]
Lin S, Liu M, Son YJ, Himes BT, Snow DM, Yu W, Baas PW
Traffic. 2011 Jan 17;12:269-286.

"Strategies for Diminishing Katanin-Based Loss of Microtubules in Tauopathic Neurodegenerative Diseases" [PDF]
Sudo H, Baas PW
Human Molecular Genetics. 2011 Feb 15;20(4):763-778.

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2006-2010

"Kinesin-12, a Mitotic Microtubule-Associated Motor Protein, Impacts Axonal Growth, Navigation, and Branching" [PDF]
Liu M, Nadar VC, Kozielski F, Kozlowska M, Yu W, Baas PW
Journal of Neuroscience. 2010 Nov 3;30(44):14896-906.

"Evaluation of Loss of Function as an Explanation for SPG4-Based Hereditary Spastic Paraplegia" [PDF]
Solowska JM, Garbern JY, Baas PW
Human Molecular Genetics. 2010 Jul 15;19(14):2767-2779.

"Acetylation of Microtubules Influences Their Sensitivity to Severing by Katanin in Neurons and Fibroblasts" [PDF]
Sudo H, Baas PW
The Journal of Neuroscience. 2010 May 26;30(21):7215-7226.

"Mechanical Breaking of Microtubules in Axons During Dynamic Stretch Injury Underlies Delayed Elasticity, Microtubule Disassembly, and Axon Degeneration" [PDF]
Tang-Schomer MD, Patel AR, Baas PW, Smith DH
FASEB Journal. 2010 May 24;(5):1401-1410.

"Basic Fibroblast Growth Factor Elicits Formation of Interstitial Axonal Branches via Enhanced Severing of Microtubules" [PDF]
Qiang L, Yu W, Liu M, Solowska JM, Baas PW
Molecular Biology of the Cell (MBoC). 2010 Jan 15;21(2):334–344.

"Doublecortin Associates with Microtubules Preferentially in Regions of the Axon displaying Actin-Rich Protrusive Structures" [PDF]
Tint I, Jean D, Baas PW, Black MM
The Journal of Neuroscience. 2009 Sept 2;29(35):10995-11010.

"The Cul3/Klhdc5 E3 Ligase Regulates p60/Katanin and Is Required for Normal Mitosis in Mammalian Cells"
Cummings CM, Bentley CA, Perdue SA, Baas PW, Singer JD
Journal of Biological Chemistry. 2009 Apr. 24;284(17):11663-11675.

"Critical Roles for Microtubules in Axonal Development and Disease"
Falnikar A, Baas PW
Results and Problems in Cell Differentiation. 2009 Apr 3;(48):47-64.

"Kinesin-5 is Essential for Growth-Cone Turning" [PDF]
Nadar VC, Ketschek A, Myers KA, Gallo G, Baas PW
Current Biology. 2008 Dec 23;18(24):1972-1977.

"The Microtubule-severing Proteins Spastin and Katanin Participate Differently in the Formation of Axonal Branches" [PDF]
Yu W, Qiang L, Solowska JM, Karabay A, Korulu S, Baas PW
Molecular Biology of the Cell. 2008 Apr ;19(4):1485-1498.

"Quantitative and Functional Analyses of Spastin in the Nervous System: Implications for Hereditary Spastic Paraplegia" [PDF]
Solowska JM, Morfini G, Falnikar A, Himes BT, Brady ST, Huang D, Baas PW
The Journal of Neuroscience. 2008 Feb 27;28(9):2147-2157.

"Kinesin-5 Regulates the Growth of the Axon by Acting as a Brake on Its Microtubule Array" [PDF]
Myers KA, Baas PW
Journal of Cell Biology. 2007 Sep 10;178(6):1081-91.

"Microtubule-Severing in the Axon: Implications for Development, Disease, and Regeneration After Injury"
Yu W, Qiang L, Baas PW
J. Environ. Biomed. 2007. 1:1-7.

"Rearrangement of Microtubule Polarity Orientation During Conversion of Dendrites to Axons in Cultured Pyramidal Neurons"
Takahashi D, Yu W, Baas PW, Kawai-Hirai R, Hayashi K
Cell Motility and the Cytoskeleton. 2007 64:347-359.

"Class III Beta-Tubulin and Gamma-Tubulin Are Co-Expressed and Form Complexes in Human Glioblastoma Cells"
Katsetos CD, Dra´berova´ E, Smejkalova B, Reddy G, Bertrand L, de Chadarevian JP, Legido A, Nissanov J, Baas PW, Draber P
Neurochemical Research. 2007 32:1387-1398.

"Antagonistic Forces Generated by Cytoplasmic Dynein and Myosin-II during Growth Cone Turning and Axonal Retraction" [PDF]
Myers KA, Tint I, Nadar CV, He Y, Black MM, Baas PW
2006. 7(10):1333-51.

"Tau-Dependent Microtubule Disassembly Initiated by Prefibrillar Beta-Amyloid" [PDF]
King ME, Kan HM , Baas PW, Erisir A, Glabe CG, Bloom GS
Journal of Cell Biology. 2006. 175:541-546.

"Tau Protects Microtubules in the Axon from Severing by Katanin" [PDF]
Qiang L, Yu W, Andreadis A, Luo M, Baas PW
The Journal of Neuroscience. March 22, 2006. 26(12):3120–3129.

"Microtubule Transport in the Axon: Re-thinking a Potential Role for the Actin"
Myers KA, He Y, Hasaka TP, Baas PW
Cytoskeleton Neuroscientist. 2006. 12(2):1-12.

"Axonal Transport of Microtubules: the Long and Short of It" [PDF]
Baas PW, Nadar CV, Myers KA
Traffic. 2006. 7:490-498.

"Effects of Dynactin Disruption and Dynein Depletion on Axonal Microtubules" [PDF]
Ahmad FJ, He Y, Myers KA, Hasaka TP, Francis F, Black MM, Baas PW
Traffic. 2006 May;7(5):524-37.

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2001-2005

"Microtubules Cut and Run" [PDF]
Baas PW, Karabay A, Qiang L
Trends Cell Biology. 2005. 15:518-524.

"Regulation of Microtubule Severing by Katanin Subunits during Neuronal Development" [PDF]
Yu W, Solowska JM, Qiang L, Karabay A, Baird D, Baas PW
The Journal of Neuroscience. 2005. 25(23):5573-5583.

"Neuronal Microtubules: When the MAP Is the Roadblock"
Baas PW, Qiang L
Trends Cell Biology. 2005. 15:183-187.

"Role of Cytoplasmic Dynein in the Axonal Transport of Microtubules and Neurofilaments" [PDF]
He Y, Frances F, Myers KA, Black M, Baas PW
Journal of Cell Biology. 2005. 168:697-703.

"Role of Actin Filaments in the Axonal Transport of Microtubules" [PDF]
Hasaka TP, Myers KA, Baas PW
Journal of Neuroscience. 2004. 24:11291-11301.

"Axonal Growth is Sensitive to the Levels of Katanin, a Protein that Severs Microtubules" [PDF]
Karabay A, Yu W, Solowska JM, Baird DH, Baas PW
Journal of Neuroscience. 2004. 24:5778-5788.

"Distribution of the Microtubule-Related Protein Ninein in Developing Neurons"
Baird DH, Myers KA, Mogensen M, Moss D, Baas PW
Neuropharmacology. 2004. 47:677-683.

"Monastrol, a Prototype Anti-Cancer Drug that Inhibits a Mitotic Kinesin, Induces Rapid Bursts of Axonal Outgrowth from Cultured Postmitotic Neurons"
Haque SA, Hasaka TP, Brooks AD, Lobanov PV, Baas PW
Cell Motility and the Cytoskeleton. 2004. 58:10-16.

"Slow Axonal Transport and the Genesis of Neuronal Morphology"
Baas PW, Buster DW
Journal of Neurobiology. 2004. 58:3-17.

"Growing and Working With Peripheral Neurons"
He Y, Baas PW
In: Methods in Cell Biology. 2003. Vol.71, pp. 17-35. Elsevier Science:USA

"Expression of the Mitotic Kinesin Kif15 in Postmitotic Neurons: Implication for Neuronal Migration and Development"
Buster DW, Baird DH, Yu W, Solowaska JM, Chauviere M, Mazurek A, Kress M, Baas PW
Journal of Neurocytology. 2003. 32:79-96.

"Microtubule Reconfiguration During Axonal Retraction Induced by Nitric Oxide" [PDF]
He Y, Yu W, Baas PW
Journal of Neuroscience. 2002. 22:5982-5991.

"Microtubule Reconfiguration During Axogenesis"
Yu W, Ling C, Baas PW
Journal of Neurocytology. 2001. 30:861-875.

"Neuronal Polarity: Microtubules Strike Back"
Baas PW
Nature Cell Biology. 4:E194-E195.

"Microtubule Transport in the Axon"
Baas PW
International Review of Cytology. 2002. 212:41-62.

"Microtubule Reconfiguration During Axogenesis"
Yu W, Ling C, Baas PW
Journal of Neurocytology. 2001. 30:861-875.

"Signaling at the Growth Cone: The Scientific Progeny of Cajal Meet in Madrid" [PDF]
Baas PW, Luo L
Neuron. 2001. 32:981-984.

"Force Generation by Cytoskeletal Motor Proteins as a Regulator of Axonal Elongation and Retraction" [PDF]
Baas PW, Ahmad FJ
Trends in Cell Biology. 2001. 11:244-249.

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1996-2000

"Depletion of a Microtubule-Associated Motor Protein Induces the Loss of Dendritic Identity" [PDF]
Yu W, Cook C, Sauter C, Kuriyama R, Kaplan PL, Baas PW
The Journal of Neuroscience. 2000. 20:5782-5781.

"Elaboration of the Axonal Microtubule Array During Development and Regeneration"
Baas PW
In: Neurobiology of Spinal Cord Injury. 2000. eds: R.G. Kalb and S.M. Strittmatter. Humana Press, Inc., Totowa, NJ. pp.155-167.

"Cytoskeleton Neuron"
Kosik KS, Baas PW
In: Elsevier's Encyclopedia of Neuroscience. 1999. 2nd edition. eds. G. Adelman and B.H. Smith. Elsevier Science B.V. pp. 509-516.

"Motor Proteins Regulate Force Interactions Between Microtubules and Microfilaments in the Axon"
Ahmad FJ, Hughey J, Wittmann T, Hyman A, Greaser M, Baas PW
Nature Cell Biology. 2000. 2:276-280.

"Reorganization and Movement of Microtubules in Axonal Growth Cones and Developing Interstitial Branches" [PDF]
Dent EW, Calloway JL, Szebenyi G, Baas PW, Kalil K
The Journal of Neuroscience. 1999. 19:8894-8908.

"An Essential Role for Katanin in Severing Microtubules in the Neuron" [PDF]
Ahmad FJ, Yu W, McNally FJ, Baas PW
Journal of Cell Biology. 1999. 145:305-315.

"Microtubules and Neuronal Polarity: Lessons From Mitosis" [PDF]
Baas PW
Neuron 22: 23-31. 1999.

"Function of a Minus-End-Directed Kinesin-Like Motor Protein in Mammalian Cells" [PDF]
Matuliene J, Essner R, Ryu JH, Hamaguchi Y, Baas PW, Haraguchi T, Hiraoka Y, Kuriyama R
J. Cell Sci. 112: 4041-4060. 1999.

"NuMA Is a Component of the Somatodendritic Microtubule Arrays of the Neuron"
Ferhat L, Cook C, Kuriyama R, Baas PW
Journal of Neurocytologyogy 27: 887-899. 1998.

"The Role of Motor Proteins in Establishing the Microtubule Arrays of Axons and Dendrites"
Baas PW
J. Chem. Neuroanat. 14: 175-180. 1998.

"Expression of the Mitotic Motor Protein Eg5 in Postmitotic Neurons: Implications for Neuronal Development" [PDF]
Ferhat L, Cook C, Chauviere M, Harper M, Kress M, Lyons GE, Baas PW
The Journal of Neuroscience. 18: 7822-7835. 1998.

"Cytoplasmic Abnormalities in Cultured Cerebellar Neurons From the Trisomy 16 Mouse"
Bersu ET, Ahmad FJ, Schwei MJ, Baas PW
Dev. Brain. Res. 109: 115-120. 1998.

"Expression of the Mitotic Motor Protein CHO1/MKLP1 in Postmitotic Neurons"
Ferhat L, Kuriyama R, Lyons GE, Micales B, Baas PW
European The Journal of Neuroscience. 10: 1383-1393. 1998.

"Cytoplasmic Dynein and Dynactin Are Required for the Transport of Microtubule Into the Axon" [PDF]
Ahmad FJ, Echeverri CJ, Vallee RB, Baas PW
Journal of Cell Biology. 140: 391-402. 1998.

"A New Strategy for Studying Microtubule Transport and Assembly During Axon Growth"
Baas PW
In Microinjection and Transgenesis of Cultured Cells and Embryos: Springer Lab Manual. (A. Cid-Arregui, Editor) Springer-Verlag, Heidelberg. pp. 155-170. 1997.

"Identification of a Microtubule-associated Motor Protein Essential for Dendritic Differentiation" [PDF]
Sharp DJ, Yu W, Ferhat L, Kuriyama R, Rueger DC, Baas PW
Journal of Cell Biology. 138: 833-843. 1997.

"Expression of a Minus-End-Directed Motor Protein Induces Sf9 Cells to Form Axon-Like Processes With Uniform Microtubule Polarity Orientation" [PDF]
Sharp DJ, Kuriyama R, Baas PW
J. Cell Sci. 110: 2373-2380. 1997.

"Slow Axonal Transport: The Polymer Transport Model" [PDF]
Baas PW, Brown A
Trends in Cell Biology 7: 380-384. 1997.

"Microtubule Organization and Stability in the Oligodendrocyte" [PDF]
Lunn KF, Baas PW, Duncan ID
The Journal of Neuroscience. 17: 4921-4932. 1997.

"Inhibition of a Mitotic Motor Compromises the Formation of Dendrite-Like Processes From Neuroblastoma Cells" [PDF]
Yu W, Sharp DJ, Kuriyama R, Malak P, Baas PW
Journal of Cell Biology. 136: 659-668. 1997.

"Microtubules and Axon Growth"
Baas PW
Current Opinion in Cell Biology 9: 29-36. 1997.

"Microtubule Assembly in Growing Dendrites" [PDF]
Wang J, Yu W, Baas PW, Black M
The Journal of Neuroscience. 16: 6065-6078. 1996.

"Expression of a Kinesin-Related Motor Protein Induces Sf9 Cells to Form Dendrite-Like Processes With Nonuniform Microtubule Polarity Orientation" [PDF]
Sharp DJ, Kuriyama R, Baas PW
The Journal of Neuroscience. 16: 4370-4375. 1996.

"A Composite Model for Establishing the Microtubule Arrays of the Neuron"
Baas PW, Yu W
Molecular Neurobiology 12: 145-161. 1996.

"The Neuronal Centrosome as a Generator of Microtubules for the Axon"
Baas PW
Current Topics in Developmental Biology 33: 281-298. 1996.

"Cytoskeletal Alterations During Neurogenesis in Cultures of Avian Neural Crest Cells"
Haendel MA, Bollinger KE, Baas PW
J. Neurocytology 25: 289-301. 1996.

"Juvenile and Mature MAP2 Isoforms Induce Distinct Patterns of Process Outgrowth"
LeClerc N, Baas PW, Garner CC, Kosik KS
Molecular Biology of the Cell 7: 443-455. 1996.

"Microtubule Transport and Assembly During Axon Growth" [PDF]
Yu W, Schwei MJ, Baas PW
Journal of Cell Biology. 133: 151-157. 1996.

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1991-1995

"The Growth of the Axon Is Not Dependent Upon Net Microtubule Assembly at Its Distal Tip" [PDF]
Yu W, Baas PW
The Journal of Neuroscience. 15: 6827-6833. 1995.

"Microtubule Released From the Neuronal Centrosome Are Transported Into the Axon" [PDF]
Ahmad FJ, Baas PW
J. Cell Sci. 108: 2761-2769. 1995.

"Transport of Dendritic Microtubules Establishes Their Nonuniform Polarity Orientation" [PDF]
Sharp DJ, Yu W, Baas PW
Journal of Cell Biology. 130: 93-104. 1995.

"Casein Kinase I Localizes to Small Synaptic Vesicles and Is Regulated by Phosphatidylinositol-4-5-Bisphosphate"
Gross SD, Hoffman DP, Baas PW, Anderson RA
Journal of Cell Biology. 130: 711-724. 1995.

"Microtubule Fragmentation and Partitioning in the Axon During Collateral Branch Formation"
Yu W, Ahmad FJ, Baas PW
The Journal of Neuroscience. 14: 5872-5884. 1994.

"An in Vitro Model for the Effects of Estrogen on Neurons Employing Estrogen Receptor-Transfected PC12 Cells" [PDF]
Lustig RH, Hua P, Yu W, Ahmad FJ, Baas PW
The Journal of Neuroscience. 14: 3945-3957. 1994.

"Changes in Microtubule Number and Length During Axon Differentiation" [PDF]
Yu W, Baas PW
The Journal of Neuroscience. 14: 2818-2829. 1994.

"Inhibition of Microtubule Nucleation at the Neuronal Centrosome Compromises Axon Growth"
Ahmad FJ, Joshi HC, Centonze VE, Baas PW
Neuron 12: 271-280. 1994.

"Tau Confers Drug-Stability but Not Cold-Stability to Microtubules in Living Cells" [PDF]
Baas PW, Pienkowski TP, Cimbalnik KA, Toyama K, Bakalis S, Ahmad FJ, Kosik KS
J. Cell Sci. 107: 135-143. 1994.

"Microtubule Nucleation and Release From the Neuronal Centrosome" [PDF]
Yu W, Centonze VE, Ahmad FJ, Baas PW
Journal of Cell Biology. 122: 349-359. 1993.

"A New Perspective on Microtubules and Axon Growth" [PDF]
Joshi HC, Baas PW
Journal of Cell Biology. 121: 1191-1196. 1993.

"Process Formation in Sf9 Cells Induced by the Expression of a MAP2C-Like Construct"
Le Clerc N, Kosik KS, Cowan N, Pienkowski TP, Baas PW
Proc. Natl. Acad. Sci. USA 90: 6223-6227. 1993.

"Regional Differences in Microtubule Dynamics in the Axon" [PDF]
Ahmad FJ, Pienkowski TP, Baas PW
The Journal of Neuroscience. 13: 856-866. 1993.

"Sites of Microtubule Stabilization for the Axon" [PDF]
Baas PW, Ahmad FJ, Pienkowski TP, Brown A, Black MM
The Journal of Neuroscience. 13: 2177-2185. 1993.

"Gamma-Tubulin Distribution in the Neuron: Implications for the Origins of Neuritic Microtubules" [PDF]
Baas PW, Joshi HC
Journal of Cell Biology. 119: 171-178. 1992.

"Improved Methods for the Use of Glass Coverslips in Cell Culture and Electron Microscopy"
Whitlon DS, Baas PW
J. Histochem. Cytochem. 40: 875-877. 1992.

"The Plus Ends of Stable Microtubules Are the Exclusive Microtubule Nuceating Structures in the Axon" [PDF]
Baas PW, Ahmad FJ
Journal of Cell Biology. 116: 1231-1241. 1992.

"Processes Induced by Tau Expression in Sf9 Cells Have an Axon-Like Microtubule Organization" [PDF]
Baas PW, Pienkowski TP, Kosik KS
Journal of Cell Biology. 115: 1333-1344. 1991.

"Microtubule Dynamics in Axons and Dendrites" [PDF]
Baas PW, Slaughter T, Brown A, Black MM
The Journal of Neuroscience. Res. 30:134-153. 1991.

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1986-1990

"Individual Microtubules in the Axon Consist of Domains That Differ in Both Composition and Stability" [PDF]
Baas PW, Black MM
Journal of Cell Biology. 111: 495-509. 1990.

"Changes in Microtubule Polarity Orientation During the Development of Hippocampal Neurons in Culture"
Baas PW, Black MM, Banker GA
Journal of Cell Biology. 109: 3085-3094. 1989.

"Compartmentation of Alpha Tubulin in the Neuron: Identification of a Somatodendritic-Specific Variant of Alpha-Tubulin"
Baas PW, Black MM
Neuroscience 30: 795-803. 1989.

"The Basis of Polarity in the Neuron"
Black MM, Baas PW
Trends in Neurosci. 12: 211-214. 1989.

"Dynamics of Alpha Tubulin Deacetylation in Cultured Neurons"
Black MM, Baas PW, Humphries S
The Journal of Neuroscience. 9: 358-368. 1989.

"Dynamics of Alpha Tubulin Deacetylation in Cultured Neurons"
Black MM, Baas PW, Humphries S
J. Neurosci. 9: 358-368. 1989.

"Polarity Orientation of Microtubules in Hippocampal Neurons: Uniformity in the Axon and Nonuniformity in the Dendrite"
Baas PW, Deitch JS, Black MM, Banker GA
Proc. Natl. Acad. Sci. USA 85: 8335-8339. 1988.

"Role of Microtubules in the Cytoplasmic Compartmentation of Neurons. II. Endocytosis in the Growth Cone and Neurite Shaft"
Sinclair GI, Baas PW, Heidemann SR
Brain Res. 450: 60-68. 1988.

"Role of Microtubules in the Cytoplasmic Compartmentation of Neurons"
Baas PW, Sinclair GI, Heidemann SR
Brain Res. 420: 73-81. 1987.

"Microtubule Stability in Severed Axons"
White LA, Baas PW, Heidemann SR
Journal of Neurocytology. 16: 775-784. 1987.

"Microtubule Polarity Reversal Accompanies Regrowth of Amputated Neurites"
Baas PW, White LA, Heidemann SR
Proc. Natl. Acad. Sci. USA 84: 5272-5276. 1987.

"The Cytoskeleton of Neurites After Microtubule Depolymerization"
Joshi HC, Baas PW, Chu DT, Heidemann SR
Exp. Cell Res. 163: 233-245. 1986.

"Microtubule Reassembly From Nucleating Fragments During the Regrowth of Amputated Neurites"
Baas PW, Heidemann SR
Journal of Cell Biology. 103: 917-927. 1986.

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Baas Lab researchers used electron tomography to construct a 3D model (bottom), and found that whereas most microtubules (green) are attached to the centrosome (blue), a small number are unattached. The unattached microtubules are able to undergo motor-driven sliding, which helps neurons migrate in a straight line.