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Marie-Pascale Côté

Marie-Pascale Côté, PhD

Assistant Professor


Department: Neurobiology & Anatomy

Education

  • BSc in Biological Science/Animal Physiology - Université de Montréal (2000)
  • MSc in Neurological Sciences - Université de Montréal (2001)
  • PhD in Neurolgoical Sciences - Université de Montréal (2007)

Dr. Côté is an assistant professor in the Department of Neurobiology & Anatomy at Drexel University College of Medicine.

Research Interests

Plasticity of spinal networks after spinal cord injury

Research

Our research focuses on plasticity of the spinal networks after spinal cord injury. We are particularly interested in the modifications that lead to impairment of motor function following injury and activity-dependent mechanisms that assist in recovery of function. Activity-based therapies are routinely integrated into rehabilitation programs to induce repetitive activation of the neuromuscular system and facilitate functional recovery after spinal cord injury. The objective of our research is to investigate how motor activity contributes to functional recovery after SCI. A better understanding of the mechanisms at play is crucial for the design of optimized rehabilitation strategies.

Projects currently funded by:

  • National Institutes of Health (NINDS)
  • Craig H. Neilsen Foundation

Publications

Recent Publications

"Exercise modulates chloride homeostasis after spinal cord injury"
Côté, M-P, Zambrotta M, Ghandi S and Houle; JD
J Neurosci., 34:8976-8987. PMID: 24990918, 2014

"Axon regeneration and exercise dependent plasticity after spinal cord injury"
Houle JD and Côté, M-P
In: Cellular and Network Functions in the Spinal Cord, Ann NY Acad Sci. 1279:154-63. PMID:
23531013, Mar 2013

"Plasticity in ascending long propriospinal and descending supraspinal pathways in chronic cervical spinal cord injured rats"
Côté, M-P, Detloff MR, Wade R, Lemay MA and Houle JD
Front. Physiol. 3:330. PMID: 22934078, August 17, 2012

"Activity-dependent increase in neurotrophic factors after SCI is correlated with an enhanced modulation of spinal reflexes"
Côté, M-P, Azzam GA, Lemay MA, Zhukareva V, Houle JD
J Neurotrauma. 28:299-309. PMID: 21083432, February 2011

"The spinal generation of phases and cycle duration. In: Breathe, Walk and Chew; the neural challenge: Part II"
Gossard J-P, Sirois J, Noué P, Côté M-P, Ménard A, Leblond H, Frigon A  
Prog. Brain Res, J-P Gossard, R Dubuc, A Kolta Eds, Elsevier, Vol. 188, pp15-29. PMID: 21333800, 2011

"Nerve Grafting for Spinal Cord Injury in Cats: Are We Close to Translational Research?"
Hanna AS, Côté, M-P, Houle JD, Dempsey R
Neurosurgery 68:NN14-NN15, April 2011

"Peripheral Nerve Grafts Support Regeneration after Spinal Cord Injury"
Côté, M-P, Amin A, Tom V, Houle JD
Neurotherapeutics 8:294-303. PMID: 21360238, April 2011

"Peripheral Nerve Grafts after Cervical Spinal Cord Injury in Adult Cats"
Côté, M-P, Hanna A, Lemay M.A., Ollivier-Lanvin K, Santi L, Miller K, Monaghan R, Houle JD
Exp Neurol 225:173-182, September 2010

"Combining Peripheral Nerve Grafting and Matrix Modulation to Repair the Injured Rat Spinal Cord"
Houle JD, Amin A, Côté, M-P, Lemay M, Miller K, Sandrow H, Santi L, Shumsky J, Tom V
J Vis Exp 33:1324. PMID: 19935638, November 20, 2009


Contact Information


Research Office

Department of Neurobiology & Anatomy
2900 W. Queen Lane
Philadelphia, PA 19129
Phone: 215.991.8598
Fax: 215.843.9082