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Daniel J. Chandler

Daniel J. Chandler, PhD

Instructor


Department: Neurobiology & Anatomy

Education

  • PhD in Neuroscience - Drexel University College of Medicine (2013)
  • BA in Neuroscience - Hamilton College (2008)

Awards & Honors

  • Amadeo Bondi Award, Drexel University College of Medicine (2014)
  • 2nd Place, Platform Presentation Competition, Discovery Day, Drexel University College of Medicine (2013)
  • 10th International Catecholamine Symposium Top Poster/Data Blitz Presenter (2012)
  • Amadeo Bondi Fellowship, Drexel University College of Medicine (2012)
  • James H. Glass Fellowship, Hamilton College (2008)
  • Elihu Root Fellowship, Hamilton College (2008)
  • Senior Prize in Neuroscience, Hamilton College (2008)

Memberships / Professional Affiliations

  • American Association for the Advancement of Science (2012)
  • Society for Neuroscience (2010)
  • Sigma Xi: The Scientific Research Society, Hamilton College Chapter (2008)
  • Psi Chi: International Honor Society in Psychology, Hamilton College Chapter (2006)

Postgraduate Training / Additional Certifications

  • Postdoctoral research, University of Pennsylvania Department of Psychiatry (2014-2015)
Daniel Chandler, PhD, is an instructor in the Department of Neurobiology & Anatomy at Drexel University College of Medicine.

Research Overview

Dr. Chandler studies the stress response of central monoaminergic projection systems. Before coming to Drexel, Dr. Chandler was a postdoctoral researcher at the University of Pennsylvania under the mentorship of Olivier Berton, PhD.

Research Interests

Organizational and functional properties of the central monoaminergic projection systems and how they adapt in response to stress

Publications

"Evidence for a specialized role of the locus coeruleus noradrenergic system in cortical circuitries and behavioral operations"
D.J. Chandler 
Brain Research, November 20, 2015

"Norepinephrine and Synaptic Transmission in the Cerebellum"
G. Zitnik, D.J. Chandler & B.D. Waterhouse
Handbook of the Cerebellum and Cereballar Disorders, Second Edition. New York: Springer, 2014

"New Perspectives on Catecholaminergic Regulation of Executive Circuits:  Evidence for Independent Modulation of Prefrontal Functions by Midbrain Dopaminergic and Noradrenergic Neurons"
D.J. Chandler, B.D. Waterhouse & W.J. Gao
Frontiers in Neural Circuits, 8(53), 2014

"Heterogeneous Organization of the Locus Coeruleus Projections to Prefrontal and Motor Cortices"
D.J. Chandler, W.J. Gao & B.D. Waterhouse
Proceedings of the National Academy of Science, 111(18): 6816-6821, 2013

"Something's got to give: psychiatric disease on the rise and novel drug development on the decline"
D.J. Chandler 
Drug Discovery Today, 18:3-4, 2012

"Identification and distribution of projections from monoaminergic and cholinergic nuclei to functionally differentiated subregions of prefrontal cortex"
D.J. Chandler, C.S. Lamperski & B.D. Waterhouse
Brain Research, 1522:38-58, 2012

"Evidence for broad versus segregated projections from cholinergic and noradrenergic nuclei to functionally and anatomically discrete subregions of prefrontal cortex"
D.J. Chandler & B.D. Waterhouse
Frontiers in Behavioral Neuroscience, 6(20), 2012

"Norepinephrine and Synaptic Transmission in the Cerebellum"
D.J. Chandler, S.E. Nicholson, G. Zitnik & B.D. Waterhouse
Handbook of the Cerebellum and Cerebellar Disorders, First Edition. New York: Springer, 2011

Presentations

Abstracts

"Electrophysiological Properties of Locus Coeruleus-Prefrontal Cortical Projection Neurons in Normal and Inattentive Rats"
B.D Waterhouse, D.J. Chandler, E.W. Prouty & W.J. Gao
American College of Neuropsychopharmacology, Phoenix, Ariz., December 2014

"Strain-specific properties of locus coeruleus projection neurons in normal and inattentive rats"
D.J. Chandler, E.W. Prouty, W.J. Gao & B.D. Waterhouse
Society for Neuroscience Conference, Washington, D.C., November 2014

"Evidence for physiological heterogeneity among projection cells in the brainstem nucleus locus coeruleus"
D.J. Chandler, W.J. Gao & B.D. Waterhouse
Gordon Research Conference: Catecholamines, West Dover, Vt., August 2013
Society for Neuroscience Conference, San Diego, Calif., November 2013

"Anatomical investigation of projections from the noradrenergic nucleus locus coeruleus to the mediodorsal thalamic nucleus in the rat"
E.W. Prouty, D.J. Chandler & B.D. Waterhouse
Drexel University College of Medicine Discovery Day, Philadelphia, Pa., October 2013

"Evidence for molecular heterogeneity among projection cells in the brainstem nucleus locus coeruleus"
D.J. Chandler & B.D.Waterhouse
Society for Neuroscience Conference, New Orleans, La., October 2012

"Axonal divergence and galanin expression in locus coeruleus neurons that project to prefrontal and motor cortices"
D.J. Chandler & B.D. Waterhouse
10th International Catecholamine Symposium, Monterey, Calif., September 2012

"Organization of monoaminergic and cholinergic efferent projections to functionally differentiated sub-regions of the prefrontal cortex"
D.J. Chandler  & B.D. Waterhouse 
Society for Neuroscience Conference, Washington, D.C., November 2011

"Medial prefrontal and orbitofrontal regions of rat cortex are innervated by distinct populations of locus coeruleus neurons"
D.J.Chandler, K.L. Agster, R.K. Vasudeva, J.A. McGaughy &  B.D. Waterhouse
Society for Neuroscience Conference, San Diego, Calif., November 2010

"Modulation of Cognitive Function by Insulin and Recurrent Hypoglycemia: Dissociations between Hippocampus, Amygdala and Frontal Cortex"
E.C. McNay, D.J. Chandler & R.S. Sherwin 
American Diabetes Association 68th Scientific Sessions, San Francisco, Calif., June 2008


Contact Information


Research Office

Department of Neurobiology & Anatomy
2900 W. Queen Lane
Philadelphia, PA 19129
Phone: 215.991.8401
Fax: 215.843.9082