PhD Candidate, Materials Science & Engineering
Drexel faculty mentors: Yury Gogotsi, Kara Spiller
Amanda Pentecost (BS Materials Science & Engineering '13) is a dual PhD candidate in Materials Science & Engineering and MS student in Biomedical Engineering. She has been an active member of Dr. Yury Gogotsi's Nanomaterials Group
at the Drexel Nanotechnology Institute since beginning her
academic career at Drexel in 2008, and is interested in developing nanoparticle-platform drug delivery systems. As an undergraduate, Amanda participated in two major collaborative projects: one with Thomas Jefferson
University's Orthopaedic Department, and another with the Shanghai
Advanced Research Institute (SARI)'s Nanomedicine and Translational
Amanda’s dissertation research focuses on using theragnostic diamond nanoparticles to increase the effectiveness of a common anti-inflammatory drug, dexamethasone, in preventing fibrous capsule formation and isolation of an implanted biomaterial. Under the guidance of Dr. Yury Gogotsi (MSE, Drexel Nanomaterials Group) and Dr. Kara Spiller (BMES, Biomaterials and Regenerative Medicine Lab), Amanda has been designing and characterizing this novel drug delivery system, as well as testing it on a cellular level.
As a 2016 Boren and Whitaker Fellow, Amanda will be conducting research with Dr. Kwangmeyung Kim at the Center for Theragnosis, housed in the Biomedical Research Institute at the Korea Institute of Science and Technology (KIST) in Seoul, South Korea. At KIST, Amanda will have access to high-level expertise and state-of-the-art microscopy and microscopic equipment needed to monitor the real-time distribution of nanoparticles within the body as well as their effectiveness in preventing fibrosis.