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Jiu Jiang

Jiu Jiang, PhD

Research Associate Professor
Department of Biology
Office: PISB 411
jiu.jiang@drexel.edu
Phone: 215.895.0548
Lab Location: PISB 411
Lab Phone: 215.895.1305

Education:

  • MS, MD, Bengbu Medical College, Bengbu, P.R. China
  • PhD, Shanghai Second Medical University, Shanghai, P.R. China
  • Post-Doc, University of Pennsylvania School of Medicine

Research Interests:

Aging is associated with decreased expansion of T cells upon stimulation. By using influenza virus, LCMV and TCR transgenic mice, I am working on the mechanisms of impairment of specific CD8 T cell response in aged mice, which may have an important implication for understanding the alteration of immune response in aged individuals.

Selected Publications:

  • Jiang J, Fisher E, and Murasko DM. 2011. CD8 T Cell Responses to Influenza Virus Infection in Aged Mice. Ageing Res Rev 10(4):422-427.
  • Williams-Bey Y, Jiang J, and Murasko DM. 2011. Expansion of Regulatory T cells in Aged Mice following Influenza Infection. Mech Ageing Dev 132 (4):163-170.
  • He S, Kato K, Jiang J, Wahl DR, Mineishi S, Fisher EM, Murasko DM, Glick GD, Zhang Y. 2011. Characterization of the Metabolic Phenotype of Rapamycin-Treated CD8+ T Cells with Augmented Ability to o Generate Long-Lasting Memory Cells. PlosOne 6 (5): e20107.
  • Fisher E, and Jiang J. 2012. Adjuvanted vaccines against influenza in the elderly. Frontiers Biol  221-226.
  • Jiang ZL, Fisher E, Jiang J. 2012. Neonatal vaccination against respiratory syncytial virus infection. Frontiers Biol  227-232.
  • Jiang J, Fisher E, and Murasko DM. 2013. Intrinsic Defects in CD8 T cells with Aging Contribute to Impaired Primary Antiviral Responses. Exp Gerontol 48 (6): 579-586.
  • Jiang J, Fisher E, and Murasko DM. 2013. Impaired specific CD8 T cell response with aging is not due to decreased expression of CD90 on TCR transgenic T cells. Immunity & Ageing 10:36 DOI: 10.1186/1742-4933-10-36.
  • Jiang J, Fisher FM, Hensley SE, Lustigman S, Murasko DM, and Shen H. 2014. Antigen Sparing and Enhanced Protection Using A Novel rOv-ASP-1 Adjuvant in Aqueous Formulation with Influenza Vaccines. Vaccine 32(23):2696-2702.
  • Concannon MA, Jiang J. 2014. The Effect of Adjuvant on Vaccine-Induced Antibody Response Against Influenza in Aged Mice. Frontiers Biol 9(2):89-94.
  • Jiang J, Fisher FM, Concannon M, Shen H, and Murasko DM. 2015. Enhanced IgG Response to Influenza Vaccine in Aged Mice with A Novel Adjuvant, rOv-ASP-1. Vaccine (Submitted).